The brain science of hearbreak. What happens to our brains when we are going through a break-up? We get into the neuroscience that helps you tell your family why it's so hard! These sources provide the scientific backing for the information presented in the podcast episode about brain regions affected during heartbreak and breakups.

SOURCES:

1. 
   Fisher, H. E., Brown, L. L., Aron, A., Strong, G., & Mashek, D. (2010). Reward, addiction, and emotion regulation systems associated with rejection in love. Journal of Neurophysiology, 104(1), 51-60. https://doi.org/10.1152/jn.00784.2009

2. Kross, E., Berman, M. G., Mischel, W., Smith, E. E., & Wager, T. D. (2011). Social rejection shares somatosensory representations with physical pain. Proceedings of the National Academy of Sciences, 108(15), 6270-6275. https://doi.org/10.1073/pnas.1102693108

3. Eisenberger, N. I. (2012). The pain of social disconnection: examining the shared neural underpinnings of physical and social pain. Nature Reviews Neuroscience, 13(6), 421-434. https://doi.org/10.1038/nrn3231

4. Najib, A., Lorberbaum, J. P., Kose, S., Bohning, D. E., & George, M. S. (2004). Regional brain activity in women grieving a romantic relationship breakup. American Journal of Psychiatry, 161(12), 2245-2256. https://doi.org/10.1176/appi.ajp.161.12.2245

5. Freed, P. J., Yanagihara, T. K., Hirsch, J., & Mann, J. J. (2009). Neural mechanisms of grief regulation. Biological Psychiatry, 66(1), 33-40. https://doi.org/10.1016/j.biopsych.2009.01.019

6. O'Connor, M. F., Wellisch, D. K., Stanton, A. L., Eisenberger, N. I., Irwin, M. R., & Lieberman, M. D. (2008). Craving love? Enduring grief activates brain's reward center. NeuroImage, 42(2), 969-972. https://doi.org/10.1016/j.neuroimage.2008.04.256

7. Bartels, A., & Zeki, S. (2000). The neural basis of romantic love. NeuroReport, 11(17), 3829-3834. https://doi.org/10.1097/00001756-200011270-00046